Complement-fixing antibodies to bedsonia organisms in Reiter's syndrome and ankylosing spondylitis.
نویسندگان
چکیده
The Bedsonia organisms, agents of the psittacosislymphogranuloma venereum-trachoma-inclusion conjunctivitis group, have been shown by serological techniques and by isolation to be the cause of a polyarthritis of sheep (Mendlowski and Segre, 1960; Storz, Shupe, Marriott, and Thornley, 1965; Norton and Storz, 1967). By similar methods, they have also been implicated in the pathogenesis of some human cases of non-specific urethritis (Jones, 1964; Pasieczny and Sommerville, 1966; Ford, 1967). In addition, several reports have suggested a relationship between these organisms and the pathogenesis of the urethritis and arthritis of Reiter's syndrome. By means of light microscopy, Siboulet and Galistin (1962) demonstrated intracellular inclusions, which were histologically compatible with Bedsonia inclusions, in the cells of the urethral exudate of three patients with Reiter's syndrome. Amor, Coste, and Delbarre (1965) demonstrated by light microscopy intracellular bodies compatible with Bedsonia inclusions in the urethral and synovial exudates of some patients with Reiter's syndrome and ankylosing spondylitis. By electron microscopy, Levy, Ryckewaert, Silvestre, Kahn, and Mitrovic (1966) demonstrated intracellular inclusions, the ultrastructure of which was similar to that of other agents of the Bedsonia group, in the synovial fluid of a single case of the dysenteric form of Reiter's syndrome. Finally, Schachter, Barnes, Jones, Engleman, and Meyer (1966) reported positive complement-fixation tests in approximately 35 per cent. of sixteen patients with Reiter's syndrome and isolation of Bedsonia agents from the joints of four of eight patients with this condition.
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 27 3 شماره
صفحات -
تاریخ انتشار 1968